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br Experimental Procedures Further details and an outline of
2021-06-24

Experimental Procedures Further details and an outline of resources used in this work can be found in Supplemental Experimental Procedures. Introduction In response to T cell-dependent (TD) antigen stimulation, antigen-specific AICAR phosphate receptor migrate to the periphery of B cell foll
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In order to gain further insights into
2021-06-23

In order to gain further insights into the role of peptidases in B. xylophilus, four cysteine proteases highly secreted by B. xylophilus (Cardoso et al., 2016) were selected four further characterisation. Materials and methods Results and discussion Structural prediction and analysis The i
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The HPV E proteins are
2021-06-23

The HPV E7 proteins are acidic oncoproteins of approximately 98–103 ibmx synthesis that contain 3 domains: the conserved region (CR) 1, CR2, and the carboxyl terminal (C-terminal) domain. The CR1 domain is necessary for cellular transformation and RB degradation in mucosal high risk HPVs. The CR2 do
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Located on the fore tarsals of the front pair of
2021-06-23

Located on the fore-tarsals of the front pair of legs, the Haller’s organ is presumed central to tick chemosensation. Recent genomic, transcriptomic and proteomic investigations have identified several families of transmembrane proteins in the forelegs of ticks that are likely involved in olfactory
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br Particle swarm optimization for NLBP br Computational
2021-06-23

Particle swarm optimization for NLBP Computational tests Conclusions Acknowledgements This work was supported by the State Key Development Program for Basic Research of China (No. 2009CB421104) and the National Natural Science Foundation of China (Nos. 50809004 & 41071323). Main Text
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Acknowledgments The authors thank Dr Vladimir Poltoratsky an
2021-06-23

Acknowledgments The authors thank Dr. Vladimir Poltoratsky and Zhihui Xiao for their help with the in vitro FRET assay. Support for this research was provided by Saint John’s University. Introduction We predicted the existence of endothelium-derived contractile factors (EDCFs) in 1982 [1]. In 1
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The new ESC guidelines incorporate data from a network
2021-06-23

The new ESC guidelines incorporate data from a network meta-analysis of 100 studies confirming that new-generation drug-eluting stents (DES) improve survival compared with medical treatment, although this has not been demonstrated in any individual study. REVASCULARIZATION IN NON–ST-ELEVATION ACU
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br Methods br Results br Discussion There
2021-06-23

Methods Results Discussion There are two particularly important facets of the present ERK findings relevant to drug conditioning. One is the strong ERK signal observed in the medial prefrontal cortex and the nucleus accumbens during the immediate post-trial interval following the final con
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br Disclosure statement br Acknowledgements This research
2021-06-23

Disclosure statement Acknowledgements This research was supported by grants from the National Institutes of Health, NS046400 and AG022971 (SD), and a fellowship from the Korea Research Foundation, KRF-2007-357-E00016 (YTK). The authors thank Dr. Barbara Crain for assistance with the immunologi
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The cytoplasmic domain of classical
2021-06-23

The cytoplasmic domain of classical cadherins is highly conserved and can interact with different cytosolic proteins. Typically this domain is associated with catenin family members, including p120 catenin, β-catenin, and α-catenin, which form a cadherin-catenin complex (Fig. 1). The catenin family
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The members in apple are similar
2021-06-22

The 8 members in apple are similar in number to the 7 in Arabidopsis and the 8 in rice, but fewer than the 10 found in mammalian species. GenBank numbers have also been reported for DGK homologues from tomato (AW035995), maize (AY106320), wheat (BT009326), a Populus cross (BU828590), grape (CB981130
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Our observation that FAK is
2021-06-22

Our observation that FAK is downregulated in vascular smooth muscle tgf beta receptor inhibitor on fibrillar collagen confirms observations reported for other cell types [14]. However, unlike the results reported previously [14], our work suggests that matrix rigidity per se does not determine FAK d
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Uracil residues incorporated into DNA exist transiently sinc
2021-06-22

Uracil residues incorporated into DNA exist transiently since they are subject to removal by the multi-step uracil-initiated DNA sphingosine australia excision repair (BER) process [2], [14]. In E. coli, uracil-DNA BER is initiated by uracil-DNA glycosylase (Ung), which catalyzes the hydrolytic cle
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Consistent with prior reports this study also found the
2021-06-22

Consistent with prior reports, this study also found the level of 11 cytokines (MIF, IL-1Ra, CTACK, M-CSF, Basic FGF, VCAM-1, SDF-1α, IL-8, IL-16, PDGF-β, and GRO-α) significantly decreased in the sera of adult HFMD patients in comparison with controls. MIF is a pro-inflammaory cytokine that is asso
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BMH-21 In conclusion adipose PGD suppressed
2021-06-22

In conclusion, adipose PGD2 suppressed the lipolysis by decreasing the intracellular cAMP level through DP2R. Therefore, PGD2 enhanced adipocyte differentiation (lipid accumulation) through both repression of the lipolysis via DP2R and activation of the lipogenesis via PPARγ. Thus, L-PGDS and DP2R a
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