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Bmp products such as Fig
2021-04-07

Bmp7 products, such as 7–9 (Fig. 2), are persistent pollutants that accumulate in the marine environment and can potentially be transferred to the human population via our trophic connections to the oceans (Wan et al., 2009). In addition to potentially addressing the mechanistic curiosities describe
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Materials and methods br Results br Discussion
2021-04-07

Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino Telotristat for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the existin
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All these results indicate that cleaving embryos
2021-04-07

All these results indicate that cleaving embryos possess a regulative mechanism, sensing the number of inner ISO-1 australia and controlling the proportion of conservative and differentiative divisions of blastomeres. The current observations agree with the results from other laboratories and our p
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br Oxidoreductase like MEM for prodrug activation br Future
2021-04-06

Oxidoreductase-like MEM for prodrug activation Future outlook Although MEM-mediated prodrug activation has been performed by different MEMs and prodrugs, and their effectiveness have been proved in vivo, only a few types of MEMs or prodrugs have been explored in prodrug activation until now [2
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As with all meta analysis this study certainly has some
2021-04-06

As with all meta-analysis, this study certainly has some limitations. First, our results were derived from unadjusted analyses due to lack of raw data, and lack of further adjusted analyses for age, gender and co-morbidity conditions may impact the reliability of our findings [63]. Second, obvious h
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The contribution of local ETA and
2021-04-06

The contribution of local ETA and ETB receptors towards heat hyperalgesia induced by inoculation of XC tumor ON 146040 in the paw of mice has been demonstrated by Baamonde and colleagues (Baamonde et al., 2004). Furthermore, using neuropathic and inflammatory nociception models, several studies ha
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The biological actions of ET are mediated via two
2021-04-06

The biological actions of ET‐1 are mediated via two distinct receptor subtypes, the endothelin A and endothelin B receptors (ETA/ETB). While activation of ETA is assumed to mediate contraction of smooth muscle cells, the activity of ETB is related to transient vasodilation [22]. In human corpus cave
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Another critical finding in this study is
2021-04-06

Another critical finding in this study is that the level of αSyn oligomers in the SN of σ1R−/− mice was progressively increased with age, whereas the levels of αSyn monomers and αSyn messenger RNA (data not shown) were not altered compared to WT mice. A number of studies reported that soluble αSyn m
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The potential impact of multiple washings on DNA retention
2021-04-06

The potential impact of multiple washings on DNA retention in semen stains had not previously been addressed. In the present study, multiple washes of semen-stained cotton cloth produced only a minimal loss of recovered DNA suggesting that multiple washes may not materially affect DNA recovery (Fig.
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br Other Alterations in Triglyceride
2021-04-06

Other Alterations in Triglyceride Metabolism in DGAT-Deficient Mice Consistent with the enzyme's ubiquitous expression pattern, DGAT deficiency also altered triglyceride metabolism in other tissues. For example, postpartum Dgat−/− female mice were unable to nurse their young owing to an absence o
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The role of ARA cyp metabolites
2021-04-06

The role of ARA-cyp450 metabolites in the liver is still unclear [44]. However, ARA-cyp450 genes metabolize other fatty acids such lauric and palmitic Cathepsin K Activity Fluorometric Assay Kit [45]. It was found that decreased cyp4a expression caused fatty livers through reduction of fatty acid
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br Materials and methods br
2021-04-06

Materials and methods Results and discussion Acknowledgements This study was supported by the Open Project Program of the Key Laboratory of Mariculture & Enhancement of Zhejiang Province (No. 2016KF003), the Key Project of Zhejiang Province (No. 2016C02055-7), and the International Science
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Higher versus lower order skills can also
2021-04-06

Higher versus lower order skills can also be understood in the context of the CPA exam. The CPA exam tests four broad topics (FAR, AUD, BEC, REG) using three different testing modes: multiple-choice, task-based simulations and written communications. Combined, the three testing modes place more emph
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Second when considering the Poisson point process the high
2021-04-06

Second, when considering the Poisson point process, the high-density or large-radius limit of the percolation probability tends to 1 exponentially fast and is governed by the isolation probability. In the random environment, the picture is more subtle since the regime of a large radius is no longer
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Besides the assessment of toxicological effects immediately
2021-04-02

Besides the assessment of toxicological effects immediately after exposure, we also studied the potential recovery of the exposed organisms, through the quantification of ChE activity at specific time intervals after placing organisms in clean test medium. Recovery from chemical challenge, in this c
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